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Total 29818 results found since Jan 2013.

Surrogate Humane Endpoints in Small Animal Models of Acute Lung Injury: A Modified Delphi Consensus Study of Researchers and Laboratory Animal Veterinarians*
Conclusions: We provide a preliminary framework that researchers and animal welfare committees may adapt for their needs. We have identified knowledge gaps that future research should address.
Source: Critical Care Medicine - January 16, 2021 Category: Emergency Medicine Tags: Pediatric Critical Care Source Type: research

Use of nutrition risk in critically ill (NUTRIC) score to assess nutritional risk in mechanically ventilated patients: A prospective observational study
Conclusions: Nearly 42.5% of MV patients admitted to ICU were at nutritional risk, and high mNUTRIC score was associated with increased ICU length of stay and higher mortality.
Source: Indian Journal of Critical Care Medicine - May 16, 2017 Category: Intensive Care Authors: MS Kalaiselvan MK Renuka AS Arunkumar Source Type: research

Pressure ulcer and nutrition
Seied Hadi Saghaleini, Kasra Dehghan, Kamran Shadvar, Sarvin Sanaie, Ata Mahmoodpoor, Zohreh OstadiIndian Journal of Critical Care Medicine 2018 22(4):283-289Pressure ulcers can diminish global life quality, contribute to rapid mortality in some patients and pose a significant cost to health-care organizations. Accordingly, their prevention and management are highly important. Nutritional deprivation and insufficient dietary intake are the key risk factors for the development of pressure ulcers and impaired wound healing. Unplanned weight loss is a major risk factor for malnutrition and pressure ulcer development. Suboptim...
Source: Indian Journal of Critical Care Medicine - April 18, 2018 Category: Intensive Care Authors: Seied Hadi Saghaleini Kasra Dehghan Kamran Shadvar Sarvin Sanaie Ata Mahmoodpoor Zohreh Ostadi Source Type: research

Case Study: Daily review of telemonitoring data by a critical care nurse improves outcomes in a patient with Class IV, Stage D heart failure with reduced ejection fraction receiving home intravenous dobutamine for palliation.
ConclusionsDaily critical care nurse telemonitoring resulted in nearly daily interventions with gradual stabilization of weight and vital signs, no decline in respiratory status, and no hospitalizations throughout 69 days of service. Of particular significance is the fact that telemonitoring improved the patient's compliance to his treatment plan, which resulted in an evaluation for a left ventricular assist device placement.
Source: Heart and Lung: The Journal of Acute and Critical Care - August 30, 2019 Category: Respiratory Medicine Source Type: research

Nutrition and Hydration in Older Adults in Critical Care
This article highlights the challenges of managing nutrition and hydration in the critically ill older adult, reviews assessment principles, and offers strategies for optimizing nutrition and hydration.
Source: Critical Care Nursing Clinics of North America - December 2, 2013 Category: Nursing Authors: Rose Ann DiMaria-Ghalili, Michele Nicolo Source Type: research

Physical, Emotional/Behavioral, and Neurocognitive Developmental Outcomes From 2 to 4 Years After PICU Admission: A Secondary Analysis of the Early Versus Late Parenteral Nutrition Randomized Controlled Trial Cohort*
CONCLUSIONS: From 2- to 4-year post-PICU admission, developmental impairments remained prominent. Within that time-window, impaired growth in height, executive functioning and intelligence aggravated, and impaired memory and harm by early-PN only partially recovered. Impact on development into adulthood requires further investigation.
Source: Pediatric Critical Care Medicine - August 1, 2022 Category: Pediatrics Tags: Feature Articles Source Type: research

The Role of Weight Management in the Treatment of Adult Obstructive Sleep Apnea. An Official American Thoracic Society Clinical Practice Guideline.
CONCLUSIONS: Weight-loss interventions, especially comprehensive lifestyle interventions, are associated with improvements in OSA severity, cardiometabolic comorbidities, and quality of life. The American Thoracic Society recommends that clinicians regularly assess weight and incorporate weight management strategies that are tailored to individual patient preferences into the routine treatment of adult patients with OSA who are overweight or obese. PMID: 30215551 [PubMed - in process]
Source: American Journal of Respiratory and Critical Care Medicine - September 15, 2018 Category: Respiratory Medicine Authors: Hudgel DW, Patel SR, Ahasic AM, Bartlett SJ, Bessesen DH, Coaker MA, Fiander PM, Grunstein RR, Gurubhagavatula I, Kapur VK, Lettieri CJ, Naughton MT, Owens RL, Pepin JD, Tuomilehto H, Wilson KC, American Thoracic Society Assembly on Sleep and Respiratory Tags: Am J Respir Crit Care Med Source Type: research

Attenuated Bordetella Pertussis Vaccine Protects against RSV Disease via an IL-17-dependent Mechanism.
Conclusions: Rather than enhancing RSV disease, BPZE1 protected against viral infection, modified viral responses and enhanced natural mucosal resistance. Prevention of RSV infection by BPZE1 appears in part to be due to induction of IL-17. PMID: 24261996 [PubMed - as supplied by publisher]
Source: American Journal of Respiratory and Critical Care Medicine - November 21, 2013 Category: Respiratory Medicine Authors: Schnoeller C, Roux X, Sawant D, Raze D, Olszewska W, Locht C, Openshaw PJ Tags: Am J Respir Crit Care Med Source Type: research

The non-allergic asthma of obesity: a matter of distal lung compliance.
Conclusions: Weight loss decompresses the lung in both obese controls and asthmatics, but the more pronounced effects of weight loss on lung elastance suggest that the distal lung is inherently more collapsible in asthmatics. PMID: 24821412 [PubMed - as supplied by publisher]
Source: American Journal of Respiratory and Critical Care Medicine - May 12, 2014 Category: Respiratory Medicine Authors: Al-Alwan A, Bates JH, Chapman D, Kaminsky DA, Desarno MJ, Irvin CG, Dixon AE Tags: Am J Respir Crit Care Med Source Type: research

Continuous Positive Airway Pressure plus Weight Loss for Obstructive Sleep Apnea (OSA), Association of Cancer with OSA, and Hypoglossal Nerve Stimulation for OSA Treatment.
PMID: 25830519 [PubMed - as supplied by publisher]
Source: American Journal of Respiratory and Critical Care Medicine - April 1, 2015 Category: Respiratory Medicine Authors: Iftikhar IH, Donley MA, Al-Jaghbeer M, Monserrate A Tags: Am J Respir Crit Care Med Source Type: research

Understanding the Anatomic Basis for Obstructive Sleep Apnea Syndrome in Adolescents.
CONCLUSIONS: Increased size of the pharyngeal lymphoid tissue, rather than enlargement of the upper airway soft tissue structures, is the primary anatomic risk factor for OSAS in obese adolescents. These results are important for clinical decision making, and suggest that adenotonsillectomy should be considered as the initial treatment for OSAS in obese adolescents, a group with poor CPAP adherence and difficulty achieving weight loss. PMID: 25835282 [PubMed - as supplied by publisher]
Source: American Journal of Respiratory and Critical Care Medicine - April 2, 2015 Category: Respiratory Medicine Authors: Schwab RJ, Kim C, Bagchi S, Keenan BT, Comyn FL, Wang S, Tapia IE, Huang S, Traylor J, Torigian DA, Bradford RM, Marcus CL Tags: Am J Respir Crit Care Med Source Type: research

Reply: Weight-Loss Effect on FVC in Nintedanib Idiopathic Pulmonary Fibrosis Trials?
PMID: 26469847 [PubMed - in process]
Source: American Journal of Respiratory and Critical Care Medicine - October 15, 2015 Category: Respiratory Medicine Authors: Richeldi L, Le Maulf F, Schlenker-Herceg R, Collard HR Tags: Am J Respir Crit Care Med Source Type: research

Weight-Loss Effect on FVC in Nintedanib Idiopathic Pulmonary Fibrosis Trials?
PMID: 26469846 [PubMed - in process]
Source: American Journal of Respiratory and Critical Care Medicine - October 15, 2015 Category: Respiratory Medicine Authors: Assaly R, Khan AR, Olson DE Tags: Am J Respir Crit Care Med Source Type: research

Circulating Plasma Extracellular Microvesicle miRNA Cargo and Endothelial Dysfunction in OSA Children.
CONCLUSIONS: These observations elucidate a novel role of exosomal miRNA-630 as a putative key mediator of vascular function and CVD risk in children with underlying OSA and/or obesity, and identify therapeutic targets. PMID: 27163713 [PubMed - as supplied by publisher]
Source: American Journal of Respiratory and Critical Care Medicine - May 9, 2016 Category: Respiratory Medicine Authors: Khalyfa A, Kheirandish-Gozal L, Khalyfa AA, Philby MF, Alonso-Álvarez ML, Mohammadi M, Bhattacharjee R, Terán-Santos J, Huang L, Andrade J, Gozal D Tags: Am J Respir Crit Care Med Source Type: research

Circulating Plasma Extracellular Microvesicle MicroRNA Cargo and Endothelial Dysfunction in Children with Obstructive Sleep Apnea.
CONCLUSIONS: These observations elucidate a novel role of exosomal miRNA-360 as a putative key mediator of vascular function and cardiovascular disease risk in children with underlying OSA and/or obesity, and identify therapeutic targets. PMID: 27163713 [PubMed - in process]
Source: American Journal of Respiratory and Critical Care Medicine - October 31, 2016 Category: Respiratory Medicine Authors: Khalyfa A, Kheirandish-Gozal L, Khalyfa AA, Philby MF, Alonso-Álvarez ML, Mohammadi M, Bhattacharjee R, Terán-Santos J, Huang L, Andrade J, Gozal D Tags: Am J Respir Crit Care Med Source Type: research